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Extension of chronological life span in yeast by decreased TOR pathway signaling

The starting dose, intended to gauge tolerance and initial response, aligns with standard practices in early-phase clinical trials where safety is paramount

Potassium depletion may be the most common, but it may also be iron, magnesium, another B vitamin etc

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ClinicalTrials.gov provides key stakeholders with a tool that they can use to ensure trial transparency and to monitor and evaluate issues of trial methodology